We have recently had the opportunity of studying a case of march hemoglobinuria in a young woman in whom attacks were precipitated by short walks. The present communication describes the clinical and ...

Discolored urine is a common reason for office visits to a primary care physician and urology referral. Early differentiation of the type or cause of discolored urine is necessary for accurate ...

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder that causes red blood cells to break down. This can lead to symptoms and complications ranging from discoloration of urine to leukemia and ...

We report the case of a female who was cured of hemorrhagic esophageal varices caused by paroxysmal nocturnal hemoglobinuria (PNH) through transjugular intrahepatic portosystemic shunt (TIPS) ...

Extracorpuscular hemolysis caused by mechanical trauma has been well described in relation to lower extremity use, such as in soldiers and runners. Terms such as "march hemoglobinuria", "foot strike ...

It might be easy to dismiss fatigue, headaches, bruising, and shortness of breath as something not necessarily serious, especially if they come and go without warning. However, abdominal pain and dark ...

THE most accurate method of study of any disease is enlightened statistical analysis of a large number of cases. However, paroxysmal nocturnal hemoglobinuria is a rare blood dyscrasia; approximately ...

Hemolysis is a common pathophysiologic process. It occurs in numerous conditions, including genetic hemoglobinopathies and malaria, the transfusion of stored red blood cells, and during therapeutic ...

This report presents the case of a 60-year-old woman who was admitted with symptoms of fatigue and poor appetite. Laboratory investigations revealed severe acute kidney injury (AKI), indicated by a ...

Paul Strübing, a German physician working at the Medical Clinic of Professor Mosier of Greifswald, first accurately described PNH in 2 papers published in 1882 1-5; however, he did not give the ...

Mary Kugler, RN, is a pediatric nurse whose specialty is caring for children with long-term or severe medical problems. PNH is diagnosed by a blood test, though other tests may be needed. People ...